Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
neuroendocrine system |
| gptkbp:abbreviation |
hypothalamic–pituitary–adrenal axis
|
| gptkbp:component |
gptkb:pituitary_gland
gptkb:adrenal_gland hypothalamus |
| gptkbp:dysregulationAssociatedWith |
gptkb:depression
gptkb:Cushing's_syndrome Addison's disease anxiety disorders |
| gptkbp:feedbackMechanism |
negative feedback by cortisol
|
| gptkbp:fullName |
hypothalamic–pituitary–adrenal axis
|
| gptkbp:function |
regulation of mood
regulation of digestion regulation of energy storage and expenditure regulation of immune system regulation of stress response |
| gptkbp:hormoneReleased |
gptkb:corticotropin-releasing_hormone
gptkb:adrenocorticotropic_hormone cortisol |
| https://www.w3.org/2000/01/rdf-schema#label |
HPA axis
|
| gptkbp:regulates |
cortisol secretion
stress adaptation |
| gptkbp:studiedIn |
neuroscience
endocrinology |
| gptkbp:bfsParent |
gptkb:HPA
|
| gptkbp:bfsLayer |
6
|