|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:SNK
Serum-inducible kinase
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
|
|
gptkbp:discoveredBy
|
Golsteyn et al.
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:Entrez_Gene_ID
|
10769
ENSG00000120699
|
|
gptkbp:expressedIn
|
gptkb:testis
brain
|
|
gptkbp:fullName
|
Polo-like kinase 2
|
|
gptkbp:function
|
gptkb:synaptic_plasticity
cell cycle regulation
serine/threonine-protein kinase activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
gptkb:GO:0004674
GO:0006468
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:20797
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PLK2
|
|
gptkbp:interactsWith
|
gptkb:alpha-synuclein
gptkb:PLK1
gptkb:PLK3
|
|
gptkbp:involvedIn
|
neuronal activity
synaptic homeostasis
|
|
gptkbp:length
|
683 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:5q11.2
chromosome 5: 55,232,000-55,255,000 (GRCh38)
|
|
gptkbp:molecularWeight
|
75 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Plk2
|
|
gptkbp:pathway
|
cell cycle
synaptic signaling
|
|
gptkbp:PDB
|
2RKU
|
|
gptkbp:phosphorylates
|
gptkb:alpha-synuclein
|
|
gptkbp:regulates
|
synaptic strength
induced by serum
regulated by neuronal activity
|
|
gptkbp:relatedTo
|
PLK family
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q9NYY3
|
|
gptkbp:bfsParent
|
gptkb:PLK
gptkb:Plk
|
|
gptkbp:bfsLayer
|
7
|