|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:tissue_plasminogen_activator
gptkb:T-PA
gptkb:t-PA
gptkb:tissue-type_plasminogen_activator
gptkb:tPA
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:approvedBy
|
gptkb:plasminogen_activator,_tissue_type
|
|
gptkbp:approvedSymbol
|
gptkb:PLAT
|
|
gptkbp:associatedWith
|
myocardial infarction
stroke
fibrinolysis
thrombolysis
|
|
gptkbp:biologicalProcess
|
blood coagulation
proteolysis
fibrinolysis
serine-type endopeptidase activity
|
|
gptkbp:encodes
|
gptkb:tissue_plasminogen_activator
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000104368
5327
GC08M042047
|
|
gptkbp:expressedIn
|
endothelial cells
|
|
gptkbp:fullName
|
gptkb:plasminogen_activator,_tissue_type
|
|
gptkbp:function
|
gptkb:serine_protease
converts plasminogen to plasmin
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:9051
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PLAT
|
|
gptkbp:length
|
32,000 bases
|
|
gptkbp:locatedOnChromosome
|
gptkb:8p11.21
8
|
|
gptkbp:medicalUse
|
recombinant tPA used as thrombolytic drug
|
|
gptkbp:numberOfExons
|
14
|
|
gptkbp:OMIM
|
173370
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Plat
|
|
gptkbp:PDB
|
gptkb:1A5I
gptkb:1A5M
gptkb:1A5N
gptkb:1A5O
gptkb:1BDA
gptkb:1RTF
gptkb:1TPA
1A5H
1A5J
1A5K
1A5L
1A5P
1A5Q
1A5R
1A5S
1A5T
1A5U
1A5V
1A5W
1A5X
1A5Y
1A5Z
|
|
gptkbp:product
|
gptkb:tPA
|
|
gptkbp:RefSeq
|
gptkb:NM_000930
|
|
gptkbp:UniProtID
|
P00750
|
|
gptkbp:bfsParent
|
gptkb:EGR1
|
|
gptkbp:bfsLayer
|
6
|