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gptkbp:instanceOf
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gptkb:protein
gptkb:enzyme
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gptkbp:activatedBy
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gptkb:phosphatidylinositol_3,4,5-trisphosphate
calcium
phosphatidylserine
diacylglycerol
|
|
gptkbp:alternativeName
|
gptkb:PKCĪ¶
Protein kinase C zeta type
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gptkbp:domain
|
gptkb:C1_domain
protein kinase domain
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|
gptkbp:EC_number
|
2.7.11.13
|
|
gptkbp:encodedBy
|
PRKCZ gene
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:kidney
brain
liver
|
|
gptkbp:familyMember
|
gptkb:protein_kinase_C_family
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
regulation of apoptosis
regulation of cell differentiation
regulation of cell proliferation
|
|
gptkbp:involves
|
gptkb:NF-kappaB_signaling_pathway
insulin signaling pathway
cell polarity regulation
|
|
gptkbp:locatedOnChromosome
|
chromosome 1p36.33
|
|
gptkbp:molecularWeight
|
74 kDa
|
|
gptkbp:orthologIn
|
mouse PKCzeta
rat PKCzeta
|
|
gptkbp:phosphorylates
|
various protein substrates
|
|
gptkbp:regulates
|
cell survival
cell migration
cell polarity
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q05513
|
|
gptkbp:bfsParent
|
gptkb:PDPK1
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PKCzeta
|