PKCzeta

GPTKB entity

Statements (40)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:activatedBy gptkb:phosphatidylinositol_3,4,5-trisphosphate
calcium
phosphatidylserine
diacylglycerol
gptkbp:alternativeName gptkb:PKCζ
Protein kinase C zeta type
gptkbp:domain gptkb:C1_domain
protein kinase domain
gptkbp:EC_number 2.7.11.13
gptkbp:encodedBy PRKCZ gene
gptkbp:expressedIn gptkb:skeletal_muscle
gptkb:kidney
brain
liver
gptkbp:familyMember gptkb:protein_kinase_C_family
gptkbp:foundIn gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:function signal transduction
regulation of apoptosis
regulation of cell differentiation
regulation of cell proliferation
https://www.w3.org/2000/01/rdf-schema#label PKCzeta
gptkbp:involves gptkb:NF-kappaB_signaling_pathway
insulin signaling pathway
cell polarity regulation
gptkbp:locatedOnChromosome chromosome 1p36.33
gptkbp:molecularWeight 74 kDa
gptkbp:orthologIn mouse PKCzeta
rat PKCzeta
gptkbp:phosphorylates various protein substrates
gptkbp:regulates cell survival
cell migration
cell polarity
gptkbp:subcellularLocation gptkb:nucleus
gptkb:cytoplasm
gptkbp:UniProtID Q05513
gptkbp:bfsParent gptkb:PDPK1
gptkbp:bfsLayer 7