|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:activatedBy
|
gptkb:Ras_protein
G-protein coupled receptors
|
|
gptkbp:alternativeName
|
gptkb:PIK3CG_protein
gptkb:phosphoinositide_3-kinase_gamma
|
|
gptkbp:biologicalProcess
|
signal transduction
cell migration
inflammatory response
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
leukocyte chemotaxis
|
|
gptkbp:catalyzes
|
phosphorylation of phosphatidylinositol-4,5-bisphosphate
|
|
gptkbp:EC_number
|
2.7.1.153
|
|
gptkbp:encodedBy
|
gptkb:PIK3CG_gene
|
|
gptkbp:formsComplexWith
|
p101 regulatory subunit
p84 regulatory subunit
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:GO_term
|
GO:0005942
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PI3K-gamma
|
|
gptkbp:involvedIn
|
cell signaling
immune response
chemotaxis
|
|
gptkbp:involves
|
gptkb:cancer
autoimmune diseases
inflammatory diseases
|
|
gptkbp:locatedIn
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:produces
|
phosphatidylinositol-3,4,5-trisphosphate
|
|
gptkbp:target
|
pharmacological inhibitors
|
|
gptkbp:UniProtID
|
gptkb:P48736
|
|
gptkbp:bfsParent
|
gptkb:IPI-549
|
|
gptkbp:bfsLayer
|
6
|