IPI-549

GPTKB entity

Statements (19)
Predicate Object
gptkbp:instanceOf small molecule
investigational drug
gptkbp:administeredBy oral route
gptkbp:CASNumber 1693758-51-8
gptkbp:chemicalFormula C24H24N6O2
gptkbp:clinicalTrialPhase Phase 1/1b
gptkbp:combinationTherapy immune checkpoint inhibitors
gptkbp:developedBy gptkb:Infinity_Pharmaceuticals
gptkbp:effect modulates tumor microenvironment
reduces immunosuppression
https://www.w3.org/2000/01/rdf-schema#label IPI-549
gptkbp:intendedUse immunotherapy
gptkbp:mechanismOfAction PI3K-gamma inhibition
gptkbp:studiedBy solid tumors
advanced cancers
gptkbp:synonym gptkb:PI3K-gamma_inhibitor_IPI-549
gptkbp:target gptkb:PI3K-gamma
gptkbp:bfsParent gptkb:PIK3CG
gptkbp:bfsLayer 5