Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:phosphatidylinositol-4,5-bisphosphate_3-kinase_catalytic_subunit_beta_isoform
gptkb:PIK3CB_protein |
| gptkbp:catalyzes |
phosphorylation of phosphatidylinositol (4,5)-bisphosphate
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
thrombosis metabolic disorders |
| gptkbp:encodedBy |
gptkb:PIK3CB_gene
|
| gptkbp:familyMember |
phosphoinositide 3-kinases
|
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| https://www.w3.org/2000/01/rdf-schema#label |
PI3K-beta
|
| gptkbp:involvedIn |
cell proliferation
cell survival cell growth cell migration cell signaling insulin signaling pathway platelet activation |
| gptkbp:locatedOnChromosome |
3q22.3
|
| gptkbp:produces |
gptkb:phosphatidylinositol_(3,4,5)-trisphosphate
|
| gptkbp:subunit |
gptkb:p110β_catalytic_subunit
gptkb:regulatory_subunit_(p85) |
| gptkbp:target |
PI3K inhibitors
|
| gptkbp:UniProtID |
O00329
|
| gptkbp:bfsParent |
gptkb:PIK3CB_(p110β)
|
| gptkbp:bfsLayer |
6
|