Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:PIK3CB
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:biologicalProcess |
kinase activity
|
| gptkbp:catalyzes |
phosphorylation of phosphatidylinositol (4,5)-bisphosphate
|
| gptkbp:component |
gptkb:phosphoinositide_3-kinase_(PI3K)_class_IA
|
| gptkbp:discoveredBy |
Jean-François Tanti et al.
|
| gptkbp:encodedBy |
gptkb:PIK3CB_gene
|
| gptkbp:expressedIn |
various tissues
|
| https://www.w3.org/2000/01/rdf-schema#label |
p110β catalytic subunit
|
| gptkbp:inhibitedBy |
AZD6482
TGX-221 |
| gptkbp:interactsWith |
p85 regulatory subunit
|
| gptkbp:involvedIn |
gptkb:PI3K/AKT_signaling_pathway
|
| gptkbp:locatedOnChromosome |
3q22
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
~122 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:role |
cell survival
metabolism cell growth insulin signaling platelet aggregation |
| gptkbp:UniProtID |
O00329
|
| gptkbp:bfsParent |
gptkb:PI3K_beta
|
| gptkbp:bfsLayer |
6
|