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gptkbp:instanceOf
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gptkb:protein
|
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gptkbp:alternativeName
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gptkb:phosphatidylinositol-4-phosphate_3-kinase_C2_domain-containing_alpha_polypeptide
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gptkbp:associatedWith
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gptkb:cancer
insulin signaling
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gptkbp:biologicalProcess
|
signal transduction
cell migration
kinase activity
endocytosis
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gptkbp:domain
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C2 domain
PI3K catalytic domain
PI3K helical domain
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gptkbp:enzymeClassification
|
gptkb:EC_2.7.1.154
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gptkbp:function
|
phosphorylates phosphatidylinositol-4-phosphate to generate phosphatidylinositol-3,4-bisphosphate
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gptkbp:gene
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gptkb:PIK3C2A
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https://www.w3.org/2000/01/rdf-schema#label
|
PI3K-C2α
|
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gptkbp:interactsWith
|
gptkb:Rab5
gptkb:clathrin
gptkb:insulin_receptor_substrate
|
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gptkbp:locatedOnChromosome
|
gptkb:chromosome_11p15.1
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gptkbp:location
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gptkb:cell_membrane
gptkb:cytoplasm
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gptkbp:memberOf
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gptkb:class_II_PI3K_family
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:regulates
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vesicle trafficking
actin cytoskeleton
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gptkbp:UniProtID
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gptkb:O00443
|
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gptkbp:bfsParent
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gptkb:Class_II_PI3K
gptkb:class_II_PI3K
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gptkbp:bfsLayer
|
5
|