Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:type_2_diabetes
insulin resistance |
| gptkbp:contains |
gptkb:pleckstrin_homology_domain
phosphotyrosine binding domain |
| gptkbp:foundIn |
animals
|
| gptkbp:function |
signal transduction
|
| gptkbp:gene |
IRS1 gene
IRS2 gene IRS3 gene IRS4 gene |
| gptkbp:hasMember |
gptkb:IRS1
gptkb:IRS2 IRS3 IRS4 |
| https://www.w3.org/2000/01/rdf-schema#label |
insulin receptor substrate
|
| gptkbp:interactsWith |
gptkb:insulin_receptor
gptkb:PI3K gptkb:Grb2 |
| gptkbp:involvedIn |
insulin signaling pathway
|
| gptkbp:memberOf |
IRS protein family
|
| gptkbp:phosphorylates |
gptkb:insulin_receptor
|
| gptkbp:bfsParent |
gptkb:PI3K-C2α
|
| gptkbp:bfsLayer |
6
|