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gptkbp:instanceOf
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gptkb:protein
gptkb:enzyme
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gptkbp:alternativeName
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gptkb:p110δ
phosphoinositide 3-kinase delta
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gptkbp:associatedWith
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autoimmune diseases
immunodeficiency
chronic lymphocytic leukemia
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gptkbp:domain
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C2 domain
helical domain
catalytic domain
PIK domain
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gptkbp:encodedBy
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gptkb:PIK3CD_gene
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gptkbp:expressedIn
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gptkb:leukocytes
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gptkbp:foundIn
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gptkb:Homo_sapiens
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gptkbp:function
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involved in PI3K/AKT signaling pathway
catalyzes phosphorylation of phosphatidylinositol (4,5)-bisphosphate
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https://www.w3.org/2000/01/rdf-schema#label
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PI3Kδ
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gptkbp:inhibitedBy
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gptkb:duvelisib
gptkb:idelalisib
gptkb:umbralisib
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gptkbp:locatedOnChromosome
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gptkb:chromosome_1p36.2
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gptkbp:molecularWeight
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~110 kDa
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gptkbp:OMIM
|
602839
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gptkbp:role
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immune system regulation
B cell development
T cell function
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gptkbp:subunit
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gptkb:class_IA_PI3K
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gptkbp:target
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gptkb:duvelisib
gptkb:idelalisib
gptkb:umbralisib
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gptkbp:UniProtID
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O00329
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gptkbp:bfsParent
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gptkb:phosphatidylinositol-4,5-bisphosphate_3-kinase_catalytic_subunit_delta_isoform
gptkb:Phosphatidylinositol_4,5-bisphosphate_3-kinase_catalytic_subunit_delta_isoform
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gptkbp:bfsLayer
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6
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