|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
PERI1
Period homolog 1
Rigui
circadian clock protein PERIOD 1
hPER1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
sleep disorders
mood disorders
sleep phase disorder
|
|
gptkbp:discoveredBy
|
gptkb:Joseph_S._Takahashi
|
|
gptkbp:encodes
|
PER1 protein
|
|
gptkbp:Entrez_Gene_ID
|
5187
|
|
gptkbp:expressedIn
|
gptkb:kidney
brain
liver
|
|
gptkbp:fullName
|
period circadian regulator 1
|
|
gptkbp:function
|
regulation of circadian rhythm
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
8847
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PER1
|
|
gptkbp:interactsWith
|
gptkb:BMAL1
gptkb:CLOCK
gptkb:CRY1
gptkb:CRY2
|
|
gptkbp:length
|
638 amino acids
|
|
gptkbp:locatedOnChromosome
|
17p13.1
|
|
gptkbp:molecularWeight
|
69 kDa
|
|
gptkbp:mutationAssociatedWith
|
familial advanced sleep phase syndrome
|
|
gptkbp:OMIM
|
602260
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInDrosophila
|
period (per)
|
|
gptkbp:orthologInMouse
|
Per1
|
|
gptkbp:pathway
|
cell cycle pathway
circadian rhythm pathway
|
|
gptkbp:phosphorylates
|
CK1δ
CK1ε
|
|
gptkbp:regulates
|
gptkb:PER3
gptkb:BMAL1
gptkb:CLOCK
gptkb:CRY1
gptkb:CRY2
gptkb:PER2
transcription
cell cycle
transcriptional feedback loop
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
O15534
|
|
gptkbp:bfsParent
|
gptkb:Suprachiasmatic_nucleus
|
|
gptkbp:bfsLayer
|
7
|