gptkbp:instanceOf
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gptkb:human
gptkb:nucleus
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gptkbp:abbreviation
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gptkb:SCN
|
gptkbp:controls
|
sleep-wake cycle
hormone secretion timing
|
gptkbp:discoveredBy
|
gptkb:Robert_Moore
gptkb:Irving_Zucker
|
gptkbp:expressedIn
|
gptkb:BMAL1
gptkb:CLOCK
gptkb:CRY1
gptkb:CRY2
gptkb:PER1
gptkb:PER2
clock genes
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gptkbp:firstDescribed
|
1972
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gptkbp:function
|
regulation of circadian rhythms
|
gptkbp:hasSynapticConnectionsWith
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brainstem
thalamus
other hypothalamic nuclei
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gptkbp:hasType
|
GABAergic neurons
vasopressin-expressing neurons
|
https://www.w3.org/2000/01/rdf-schema#label
|
Suprachiasmatic nucleus
|
gptkbp:influenced
|
autonomic nervous system
endocrine system
behavioral rhythms
|
gptkbp:lesionCauses
|
loss of circadian rhythms
|
gptkbp:locatedIn
|
gptkb:anterior_hypothalamus
brain
|
gptkbp:modulatedBy
|
cortisol secretion
pineal gland activity
sleep architecture
|
gptkbp:namedAfter
|
location above the optic chiasm
|
gptkbp:notableProject
|
gptkb:paraventricular_nucleus
gptkb:subparaventricular_zone
|
gptkbp:numberOfNeurons
|
about 20,000 in humans
|
gptkbp:partOf
|
hypothalamus
|
gptkbp:receivesInputFrom
|
gptkb:intergeniculate_leaflet
gptkb:retinohypothalamic_tract
gptkb:serotonergic_raphe_nuclei
retina
|
gptkbp:regulates
|
feeding behavior
body temperature rhythms
hormonal rhythms
melatonin secretion
|
gptkbp:requires
|
maintenance of circadian rhythms
|
gptkbp:shape
|
paired, oval-shaped cluster
|
gptkbp:species
|
gptkb:human
mammals
|
gptkbp:bfsParent
|
gptkb:Circadian_rhythm_disorders
|
gptkbp:bfsLayer
|
6
|