Suprachiasmatic nucleus

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:human
gptkb:nucleus
gptkbp:abbreviation gptkb:SCN
gptkbp:controls sleep-wake cycle
hormone secretion timing
gptkbp:discoveredBy gptkb:Robert_Moore
gptkb:Irving_Zucker
gptkbp:expressedIn gptkb:BMAL1
gptkb:CLOCK
gptkb:CRY1
gptkb:CRY2
gptkb:PER1
gptkb:PER2
clock genes
gptkbp:firstDescribed 1972
gptkbp:function regulation of circadian rhythms
gptkbp:hasSynapticConnectionsWith brainstem
thalamus
other hypothalamic nuclei
gptkbp:hasType GABAergic neurons
vasopressin-expressing neurons
https://www.w3.org/2000/01/rdf-schema#label Suprachiasmatic nucleus
gptkbp:influenced autonomic nervous system
endocrine system
behavioral rhythms
gptkbp:lesionCauses loss of circadian rhythms
gptkbp:locatedIn gptkb:anterior_hypothalamus
brain
gptkbp:modulatedBy cortisol secretion
pineal gland activity
sleep architecture
gptkbp:namedAfter location above the optic chiasm
gptkbp:notableProject gptkb:paraventricular_nucleus
gptkb:subparaventricular_zone
gptkbp:numberOfNeurons about 20,000 in humans
gptkbp:partOf hypothalamus
gptkbp:receivesInputFrom gptkb:intergeniculate_leaflet
gptkb:retinohypothalamic_tract
gptkb:serotonergic_raphe_nuclei
retina
gptkbp:regulates feeding behavior
body temperature rhythms
hormonal rhythms
melatonin secretion
gptkbp:requires maintenance of circadian rhythms
gptkbp:shape paired, oval-shaped cluster
gptkbp:species gptkb:human
mammals
gptkbp:bfsParent gptkb:Circadian_rhythm_disorders
gptkbp:bfsLayer 6