Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
growth factor |
| gptkbp:alternativeName |
platelet-derived growth factor subunit B homodimer
|
| gptkbp:binds |
gptkb:PDGF_receptor_alpha
gptkb:PDGF_receptor_beta |
| gptkbp:composedOf |
two PDGF-B chains
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
PDGFB gene
|
| gptkbp:form |
homodimer
heterodimer with PDGF-A |
| gptkbp:function |
stimulates cell proliferation
involved in wound healing promotes angiogenesis stimulates cell migration |
| https://www.w3.org/2000/01/rdf-schema#label |
PDGF-BB
|
| gptkbp:molecularWeight |
~24 kDa
|
| gptkbp:recipient |
gptkb:receptor_tyrosine_kinase
|
| gptkbp:role |
gptkb:cancer
atherosclerosis diabetic retinopathy fibrosis |
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:structure |
homodimer
|
| gptkbp:subunit |
gptkb:platelet-derived_growth_factor
|
| gptkbp:usedIn |
biomedical research
tissue engineering regenerative medicine |
| gptkbp:bfsParent |
gptkb:PDGFRβ
gptkb:PDGFR-beta gptkb:PDGF_receptor_alpha gptkb:PDGF_receptor_beta |
| gptkbp:bfsLayer |
7
|