Neuroblastoma

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkb:disease
gptkbp:affects children
gptkbp:associatedWith gptkb:ALK
gptkb:PHOX2B
gptkbp:canMetastasizeTo gptkb:bone
gptkb:skin
liver
lymph nodes
gptkbp:canRegressSpontaneously yes
gptkbp:cause gptkb:opsoclonus-myoclonus_syndrome
gptkb:paraneoplastic_syndromes
gptkbp:clinicalTrialPhase gptkb:Children's_Oncology_Group
gptkbp:color gold ribbon
gptkbp:commonAgeOfDiagnosis under 5 years
gptkbp:diagnosedBy imaging
biopsy
urine catecholamines
gptkbp:firstDescribed 1864
gptkbp:hasAwarenessMonth September
https://www.w3.org/2000/01/rdf-schema#label Neuroblastoma
gptkbp:ICD-10_code C74.9
gptkbp:incidence about 1 in 7,000 live births
gptkbp:marking elevated homovanillic acid
elevated vanillylmandelic acid
gptkbp:mayPresentWith gptkb:Horner's_syndrome
hypertension
proptosis
gptkbp:mortalityRate high in advanced stages
gptkbp:mostCommonSolidTumorIn infants
gptkbp:originatedIn gptkb:neural_crest_cells
gptkbp:prognosis gptkb:theatre
age at diagnosis
MYCN amplification
gptkbp:riskFactor family history
genetic mutations
gptkbp:stagingSystem gptkb:INSS
INRG
gptkbp:symptom fever
weight loss
bone pain
abdominal mass
gptkbp:treatment surgery
radiation therapy
chemotherapy
immunotherapy
stem cell transplant
gptkbp:website adrenal glands
sympathetic nervous system
gptkbp:bfsParent gptkb:Threonine_58
gptkbp:bfsLayer 7