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gptkbp:instanceOf
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gptkb:protein
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gptkbp:accessionNumber
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gptkb:NP_002037.2
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gptkbp:alternativeName
|
gptkb:HER1
Proto-oncogene c-ErbB-1
Receptor tyrosine-protein kinase ErbB-1
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|
gptkbp:associatedWith
|
various cancers
|
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gptkbp:encodedBy
|
gptkb:EGFR_gene
|
|
gptkbp:Entrez_Gene_ID
|
1956
|
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gptkbp:function
|
Tyrosine kinase activity
Receptor for members of the epidermal growth factor family
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NP 002037.2
|
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gptkbp:involvedIn
|
cell differentiation
cell proliferation
signal transduction
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|
gptkbp:locatedOnChromosome
|
gptkb:7p11.2
|
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gptkbp:molecularWeight
|
134 kDa (approximate)
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:protein_name
|
Epidermal growth factor receptor precursor
|
|
gptkbp:referenceGenome
|
NM_005228.5
|
|
gptkbp:refersTo
|
human EGFR protein isoform 1 precursor
|
|
gptkbp:sequence
|
1210 amino acids
|
|
gptkbp:subcellularLocation
|
gptkb:endosome
gptkb:cell_membrane
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:P00533
|
|
gptkbp:bfsParent
|
gptkb:P49327
gptkb:P04424
|
|
gptkbp:bfsLayer
|
7
|