|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:MnSOD
|
|
gptkbp:associatedWith
|
gptkb:cancer
amyotrophic lateral sclerosis
cardiomyopathy
|
|
gptkbp:biologicalProcess
|
response to oxidative stress
superoxide dismutase activity
metal ion binding
cellular response to superoxide
|
|
gptkbp:cofactor
|
manganese
|
|
gptkbp:disulfideBond
|
no
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000361445
GC06P160251
|
|
gptkbp:enzymeCommissionNumber
|
1.15.1.1
|
|
gptkbp:evidence_at_protein_level
|
yes
|
|
gptkbp:function
|
dismutates superoxide radicals
|
|
gptkbp:gene
|
gptkb:SOD2
|
|
gptkbp:hasIsoform
|
P22303-1
P22303-2
|
|
gptkbp:HGNC_ID
|
11179
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P22303 (human)
|
|
gptkbp:KEGGID
|
hsa:6648
|
|
gptkbp:locatedOnChromosome
|
6
6q25.3
|
|
gptkbp:location
|
mitochondrion
|
|
gptkbp:molecularWeight
|
24,713 Da
|
|
gptkbp:OMIM
|
147460
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
metabolism
detoxification of reactive oxygen species
|
|
gptkbp:PDB
|
gptkb:1QNK
gptkb:1LUV
gptkb:1N0J
|
|
gptkbp:postTranslationalModification
|
phosphorylation
methylation
acetylation
|
|
gptkbp:protein_name
|
Superoxide dismutase [Mn], mitochondrial
|
|
gptkbp:proteinFamily
|
gptkb:iron/manganese_superoxide_dismutase_family
PF00081
|
|
gptkbp:Reactome
|
gptkb:R-HSA-3299685
|
|
gptkbp:RefSeq
|
NP_000627.2
|
|
gptkbp:sequence
|
222
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:signalPeptide
|
yes
|
|
gptkbp:STRING
|
9606.ENSP00000361445
|
|
gptkbp:subcellularLocation
|
mitochondrial matrix
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:transit_peptide
|
mitochondrial
|
|
gptkbp:UniGene
|
Hs.654
|
|
gptkbp:UniProtID
|
gptkb:P22303
|
|
gptkbp:bfsParent
|
gptkb:Acetylcholinesterase
|
|
gptkbp:bfsLayer
|
7
|