|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Beta-globin
gptkb:Beta_chain_of_hemoglobin
gptkb:Hemoglobin_beta_chain
|
|
gptkbp:associated_variant
|
gptkb:CD26_(HbE_mutation)
gptkb:CD39_(HbC_mutation)
gptkb:E6V_(sickle_cell_mutation)
|
|
gptkbp:associatedWith
|
gptkb:sickle_cell_anemia
gptkb:beta-thalassemia
|
|
gptkbp:biologicalProcess
|
oxygen transport
oxygen transporter activity
|
|
gptkbp:cellularComponent
|
gptkb:hemoglobin_complex
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000335295
|
|
gptkbp:expressedIn
|
erythrocyte
|
|
gptkbp:firstDescribed
|
1950s
|
|
gptkbp:function
|
binds heme
binds oxygen
|
|
gptkbp:gene
|
gptkb:HBB
|
|
gptkbp:HGNC_ID
|
4827
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P20226
|
|
gptkbp:InterPro
|
IPR002338
|
|
gptkbp:KEGGID
|
gptkb:hsa:3043
|
|
gptkbp:locatedOnChromosome
|
11
11p15.4
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:mass_(Da)
|
15998
|
|
gptkbp:OMIM
|
141900
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Bos_taurus_HBB
gptkb:Mus_musculus_Hbb-b1
gptkb:Pan_troglodytes_HBB
|
|
gptkbp:PDB
|
gptkb:4HHB
1A3N
2H35
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:protein_name
|
gptkb:Hemoglobin_subunit_beta
|
|
gptkbp:proteinFamily
|
PF00042
|
|
gptkbp:Reactome
|
gptkb:R-HSA-1237044
|
|
gptkbp:RefSeq
|
gptkb:NP_000509.1
|
|
gptkbp:reviewedBy
|
yes
|
|
gptkbp:sequence
|
147
|
|
gptkbp:subunit
|
tetramer (2 alpha, 2 beta chains)
|
|
gptkbp:UniGene
|
gptkb:Hs.654592
|
|
gptkbp:UniProtID
|
gptkb:P20226
|
|
gptkbp:bfsParent
|
gptkb:TBP
|
|
gptkbp:bfsLayer
|
6
|