|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:allostericProtein
|
true
|
|
gptkbp:alternativeName
|
gptkb:Haemoglobin
Hb
|
|
gptkbp:associatedWith
|
gptkb:sickle_cell_anemia
gptkb:anemia
|
|
gptkbp:binds
|
oxygen
carbon dioxide
|
|
gptkbp:BohrEffect
|
true
|
|
gptkbp:clinicalTrialPhase
|
hemoglobin electrophoresis
|
|
gptkbp:color
|
red
|
|
gptkbp:component
|
hemoglobin
|
|
gptkbp:contains
|
heme group
globin protein
|
|
gptkbp:degradationSite
|
spleen
|
|
gptkbp:discoveredBy
|
gptkb:Friedrich_Ludwig_Hünefeld
|
|
gptkbp:discoveredIn
|
1840
|
|
gptkbp:EC_number
|
none
|
|
gptkbp:foundIn
|
vertebrates
human blood
|
|
gptkbp:function
|
oxygen transport
carbon dioxide transport
|
|
gptkbp:gene
|
gptkb:HBB
gptkb:HBA1
gptkb:HBA2
|
|
gptkbp:glycatedForm
|
gptkb:HbA1c
|
|
gptkbp:hemeType
|
gptkb:heme_b
|
|
gptkbp:HillCoefficient
|
2.8-3.0
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
hemoglobin complex
|
|
gptkbp:location
|
cytoplasm of erythrocytes
|
|
gptkbp:measures
|
complete blood count
|
|
gptkbp:metalIon
|
iron
|
|
gptkbp:molecularWeight
|
~64,500 Da
|
|
gptkbp:mutationAssociatedWith
|
hemoglobinopathies
|
|
gptkbp:oxidizedForm
|
methemoglobin
|
|
gptkbp:PDB
|
1A3N
|
|
gptkbp:quaternaryStructure
|
tetrameric
|
|
gptkbp:range
|
12.1–15.1 g/dL (female)
13.8–17.2 g/dL (male)
|
|
gptkbp:solubility
|
water soluble
|
|
gptkbp:structure
|
tetramer
|
|
gptkbp:subunit
|
gptkb:alpha_globin
gptkb:beta_globin
|
|
gptkbp:subunitCount
|
4
|
|
gptkbp:synthesisSite
|
bone marrow
|
|
gptkbp:transportedMolecule
|
gptkb:O2
NO
CO2
|
|
gptkbp:bfsParent
|
gptkb:HBA2_gene
|
|
gptkbp:bfsLayer
|
6
|