|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:HBB
beta-globin
|
|
gptkbp:associatedWith
|
gptkb:sickle_cell_anemia
gptkb:hemoglobin_C_disease
gptkb:hemoglobin_E_disease
|
|
gptkbp:component
|
hemoglobin
|
|
gptkbp:discoveredBy
|
gptkb:Max_Perutz
|
|
gptkbp:discoveredIn
|
1959
|
|
gptkbp:encodedBy
|
gptkb:HBB_gene
|
|
gptkbp:Entrez_Gene_ID
|
3043
|
|
gptkbp:expressedIn
|
adult stage
erythroid cells
|
|
gptkbp:formsComplexWith
|
gptkb:hemoglobin_alpha_chain
|
|
gptkbp:foundIn
|
hemoglobin
|
|
gptkbp:function
|
oxygen transport
|
|
gptkbp:hasVariant
|
gptkb:HbC
gptkb:HbE
gptkb:HbS
HbD
HbO-Arab
|
|
gptkbp:HGNC_ID
|
4827
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Hemoglobin beta chain
|
|
gptkbp:involvedIn
|
heme binding
CO2 transport
pH buffering
|
|
gptkbp:ligand
|
iron
oxygen
carbon dioxide
carbon monoxide
hemoglobin
|
|
gptkbp:locatedOnChromosome
|
chromosome 11
|
|
gptkbp:molecularWeight
|
15.9 kDa
|
|
gptkbp:mutationAssociatedWith
|
sickle cell disease
beta thalassemia
|
|
gptkbp:OMIM
|
141900
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Pan_troglodytes
|
|
gptkbp:PDB
|
1A3N
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:replacedBy
|
hemoglobin gamma chain (after birth)
|
|
gptkbp:sequence
|
146 amino acids
|
|
gptkbp:structure
|
globin fold
|
|
gptkbp:subunit
|
hemoglobin tetramer
|
|
gptkbp:UniProtID
|
P68871
|
|
gptkbp:bfsParent
|
gptkb:P20226
|
|
gptkbp:bfsLayer
|
7
|