|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
gptkb:sickle_cell_anemia
gptkb:hemoglobin_C_disease
gptkb:hemoglobin_E_disease
beta thalassemia major
beta thalassemia minor
hemoglobin D disease
hemoglobin Lepore syndrome
hemoglobin O-Arab disease
|
|
gptkbp:component
|
hemoglobin
|
|
gptkbp:determines
|
X-ray crystallography
|
|
gptkbp:discoveredBy
|
gptkb:Max_Perutz
|
|
gptkbp:encodedBy
|
gptkb:HBB_gene
|
|
gptkbp:Entrez_Gene_ID
|
3043
|
|
gptkbp:expressedIn
|
adult stage
spleen
bone marrow
erythroid cells
|
|
gptkbp:family
|
globin family
|
|
gptkbp:formsComplexWith
|
gptkb:alpha-globin
|
|
gptkbp:foundIn
|
hemoglobin
|
|
gptkbp:function
|
oxygen transport
|
|
gptkbp:gene
|
gptkb:HBB
|
|
gptkbp:hasPseudogene
|
gptkb:HBBP1
HBBP2
|
|
gptkbp:hasVariant
|
gptkb:HbC
gptkb:HbE
gptkb:HbS
Hb Lepore
HbD
HbO-Arab
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Beta-globin
|
|
gptkbp:locatedOnChromosome
|
chromosome 11
|
|
gptkbp:molecularWeight
|
approximately 16 kDa
|
|
gptkbp:mutationAssociatedWith
|
sickle cell disease
beta thalassemia
|
|
gptkbp:notExpressedDuring
|
fetal stage
|
|
gptkbp:OMIM
|
141900
|
|
gptkbp:orthologIn
|
gptkb:lion
gptkb:mouse
gptkb:zebrafish
|
|
gptkbp:partOf
|
gptkb:hemoglobin_A
|
|
gptkbp:PDB
|
1A3N
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
glycation
|
|
gptkbp:replacedBy
|
gamma-globin (in fetal hemoglobin)
|
|
gptkbp:sequence
|
146 amino acids
|
|
gptkbp:subunit
|
hemoglobin tetramer
|
|
gptkbp:UniProtID
|
P68871
|
|
gptkbp:bfsParent
|
gptkb:P20226
|
|
gptkbp:bfsLayer
|
7
|