Oncogene

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:gene
Biological concept
gptkbp:activatedBy gptkb:Mutation
Chromosomal translocation
Gene amplification
Overexpression
gptkbp:cause gptkb:cancer
Uncontrolled cell division
gptkbp:defines A gene that has the potential to cause cancer
gptkbp:example gptkb:BCR-ABL
gptkb:RAS
gptkb:SRC
gptkb:BRAF
gptkb:MYC
HER2
gptkbp:firstDescribed gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop
1976
gptkbp:hasJournal gptkb:Oncogene_(journal)
https://www.w3.org/2000/01/rdf-schema#label Oncogene
gptkbp:opposedBy Tumor suppressor gene
gptkbp:relatedTo Proto-oncogene
gptkbp:role Cellular proliferation
Tumorigenesis
gptkbp:studiedIn Oncology
Molecular biology
gptkbp:target Cancer therapies
gptkbp:bfsParent gptkb:Der,_Channing_J.
gptkb:CDK6
gptkbp:bfsLayer 7