|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:5-HTT
gptkb:SERT
|
|
gptkbp:associatedWith
|
gptkb:Autism_spectrum_disorder
gptkb:Anxiety
Depression
Obsessive-compulsive disorder
Irritable bowel syndrome
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000108576
6532
|
|
gptkbp:function
|
Serotonin reuptake transporter
|
|
gptkbp:gene
|
gptkb:SLC6A4
|
|
gptkbp:GO
|
neurotransmitter transport
serotonin uptake
serotonin:sodium symporter activity
|
|
gptkbp:HGNC_ID
|
11050
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
O00499
|
|
gptkbp:length
|
630 amino acids
|
|
gptkbp:locatedOnChromosome
|
17
|
|
gptkbp:molecularWeight
|
70,000 Da
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
5I6X
6AWN
6DZZ
|
|
gptkbp:RefSeq
|
NP_001036.2
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:subcellularLocation
|
gptkb:Cell_membrane
Multi-pass membrane protein
|
|
gptkbp:targetOfDrug
|
Selective serotonin reuptake inhibitors (SSRIs)
|
|
gptkbp:tissue_specificity
|
gptkb:Brain
gptkb:Placenta
Lung
Intestine
|
|
gptkbp:transmembraneDomains
|
12
|
|
gptkbp:UniProt_entry_name
|
gptkb:Sodium-dependent_serotonin_transporter
|
|
gptkbp:UniProtID
|
gptkb:O00499
|
|
gptkbp:bfsParent
|
gptkb:DNM2_gene
gptkb:amphiphysin
|
|
gptkbp:bfsLayer
|
7
|