|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:DNM2
DYN2
|
|
gptkbp:associatedWith
|
gptkb:Charcot-Marie-Tooth_disease
gptkb:centronuclear_myopathy
|
|
gptkbp:discoveredBy
|
1997
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000137768
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:function
|
GTPase activity
membrane fission
|
|
gptkbp:gene
|
gptkb:DNM2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dynamin 2
|
|
gptkbp:interactsWith
|
gptkb:clathrin
gptkb:amphiphysin
gptkb:endophilin
|
|
gptkbp:involves
|
vesicle trafficking
endocytosis
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
|
|
gptkbp:location
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
100 kDa
|
|
gptkbp:mutationAssociatedWith
|
neuromuscular disorders
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Dnm2
|
|
gptkbp:PDB
|
2X2E
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:RefSeq
|
NM_001005360
|
|
gptkbp:reviewedBy
|
gptkb:Nature_Reviews_Molecular_Cell_Biology
gptkb:Journal_of_Biological_Chemistry
|
|
gptkbp:structure
|
contains PH domain
contains GTPase domain
contains GED domain
contains PRD domain
|
|
gptkbp:UniProtID
|
gptkb:O00499
|
|
gptkbp:bfsParent
|
gptkb:Dynamin_family
|
|
gptkbp:bfsLayer
|
7
|