Norepinephrine transporter

URI: https://gptkb.org/entity/Norepinephrine_transporter

GPTKB entity

Statements (62)

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:solute_carrier_family
gptkbp:alternativeName	gptkb:NET gptkb:noradrenaline_transporter gptkb:solute_carrier_family_6_member_2
gptkbp:expressedIn	gptkb:locus_coeruleus gptkb:adrenal_medulla sympathetic neurons
gptkbp:foundIn	presynaptic neuron membrane
gptkbp:function	reuptake of dopamine reuptake of norepinephrine reuptake of epinephrine
gptkbp:gene	gptkb:SLC6A2
gptkbp:HGNC_ID	11049
https://www.w3.org/2000/01/rdf-schema#label	Norepinephrine transporter
gptkbp:locatedIn	central nervous system peripheral nervous system
gptkbp:locatedOnChromosome	gptkb:16q12.2
gptkbp:mechanismOfAction	sodium-dependent symporter chloride-dependent symporter
gptkbp:molecularWeight	~70 kDa
gptkbp:mutationAssociatedWith	gptkb:orthostatic_intolerance autonomic failure
gptkbp:OMIM	163970
gptkbp:significance	gptkb:depression gptkb:attention_deficit_hyperactivity_disorder gptkb:orthostatic_intolerance autonomic dysfunction
gptkbp:target	gptkb:ephedrine gptkb:tricyclic_antidepressants gptkb:bupropion gptkb:venlafaxine gptkb:desipramine gptkb:levomilnacipran gptkb:milnacipran gptkb:phentermine gptkb:tapentadol gptkb:MDMA gptkb:duloxetine gptkb:SNRIs gptkb:atomoxetine gptkb:modafinil gptkb:reboxetine gptkb:methylphenidate gptkb:pseudoephedrine gptkb:mephedrone cocaine amphetamine phenylethylamine mazindol cathinone sibutramine phenmetrazine maprotiline methylone norepinephrine reuptake inhibitors
gptkbp:transportation	dopamine norepinephrine epinephrine
gptkbp:UniProtID	P23975
gptkbp:bfsParent	gptkb:DB01452
gptkbp:bfsLayer	7