|
gptkbp:instanceOf
|
gptkb:drug
alkaloid
stimulant
sympathomimetic amine
|
|
gptkbp:ATCCode
|
R03CA02
|
|
gptkbp:CASNumber
|
299-42-3
|
|
gptkbp:chemicalFormula
|
C10H15NO
|
|
gptkbp:chirality
|
chiral
|
|
gptkbp:contraindication
|
pregnancy
hypertension
coronary artery disease
hyperthyroidism
|
|
gptkbp:controlledSubstanceSchedule
|
gptkb:Australia
gptkb:Canada
gptkb:United_States
|
|
gptkbp:discoveredBy
|
gptkb:Nagai_Nagayoshi
|
|
gptkbp:discoveredIn
|
1885
|
|
gptkbp:eliminationHalfLife
|
3-6 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:foundIn
|
gptkb:Ephedra_plant
|
|
gptkbp:has_stereochemistry
|
gptkb:D-ephedrine
gptkb:L-ephedrine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ephedrine
|
|
gptkbp:improves
|
release of dopamine
release of norepinephrine
release of serotonin
|
|
gptkbp:isomerOf
|
gptkb:pseudoephedrine
|
|
gptkbp:IUPACName
|
(1R,2S)-2-methylamino-1-phenylpropan-1-ol
|
|
gptkbp:legalStatus
|
prescription only (in many countries)
|
|
gptkbp:mechanismOfAction
|
adrenergic receptor agonist
|
|
gptkbp:meltingPoint
|
34-40 °C
|
|
gptkbp:MeSH_ID
|
D004805
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
165.23 g/mol
|
|
gptkbp:origin
|
gptkb:Ephedra_sinica
|
|
gptkbp:predecessor
|
amphetamine
methcathinone
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1547
5641
DB01364
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
subcutaneous
intravenous
|
|
gptkbp:sideEffect
|
anxiety
hypertension
increased heart rate
insomnia
|
|
gptkbp:solubility
|
freely soluble
|
|
gptkbp:traditionalUse
|
gptkb:traditional_medicine
|
|
gptkbp:UNII
|
YB7SIR7YFN
|
|
gptkbp:usedAs
|
performance-enhancing drug
|
|
gptkbp:usedFor
|
bronchodilation
treatment of hypotension
treatment of nasal congestion
|
|
gptkbp:bfsParent
|
gptkb:ECA_stack
gptkb:amphetamine
|
|
gptkbp:bfsLayer
|
6
|