pseudoephedrine

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkb:drug
gptkbp:abusePotential can be used in illicit methamphetamine synthesis
gptkbp:ATCCode R01BA02
gptkbp:bioavailability 90-100%
gptkbp:brand gptkb:Sudafed
gptkb:Dimetapp
gptkb:Actifed
gptkb:Contac
gptkbp:CASNumber 90-82-4
gptkbp:chemicalFormula C10H15NO
gptkbp:contraindication severe hypertension
severe coronary artery disease
concurrent use of MAO inhibitors
gptkbp:controlledSubstanceStatus regulated due to use in methamphetamine production
gptkbp:discoveredIn 1889
gptkbp:drugClass decongestant
sympathomimetic
gptkbp:eliminationHalfLife 4.3-8 hours
gptkbp:excretion kidneys
gptkbp:firstSynthesized gptkb:Nagayoshi_Nagai
gptkbp:foundIn combination cold medications
gptkbp:has_stereochemistry gptkb:ephedrine
https://www.w3.org/2000/01/rdf-schema#label pseudoephedrine
gptkbp:IUPACName (1S,2S)-2-methylamino-1-phenylpropan-1-ol
gptkbp:KEGGID D08414
gptkbp:legalStatus prescription only (in some countries)
over-the-counter (in some countries)
gptkbp:mechanismOfAction alpha-adrenergic receptor agonist
beta-adrenergic receptor agonist
gptkbp:meltingPoint 119-120°C
gptkbp:MeSH_ID D011563
gptkbp:metabolism liver
gptkbp:molecularWeight 165.23 g/mol
gptkbp:pregnancyCategory C (US)
gptkbp:PubChem_CID 7028
CHEMBL1201201
gptkbp:relatedTo gptkb:ephedrine
gptkb:phenylephrine
gptkbp:routeOfAdministration oral
gptkbp:sideEffect headache
nervousness
insomnia
increased blood pressure
gptkbp:solubility soluble in water
gptkbp:UNII Y6MZ3XLO3S
gptkbp:usedFor nasal congestion
allergic rhinitis
sinus congestion
gptkbp:bfsParent gptkb:amphetamine
gptkbp:bfsLayer 6