|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:approvedBy
|
gptkb:FDA
2000
|
|
gptkbp:ATCCode
|
A02BC05
|
|
gptkbp:availableOn
|
gptkb:tablet
capsule
injection
oral suspension
|
|
gptkbp:brand
|
esomeprazole
|
|
gptkbp:chemicalFormula
|
C17H19N3O3S
|
|
gptkbp:contraindication
|
hypersensitivity to esomeprazole
|
|
gptkbp:drugClass
|
proton pump inhibitor
|
|
gptkbp:eliminationHalfLife
|
1-1.5 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:genericAvailable
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Nexium
|
|
gptkbp:interactsWith
|
gptkb:warfarin
gptkb:clopidogrel
gptkb:methotrexate
gptkb:diazepam
gptkb:digoxin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:manufacturer
|
gptkb:AstraZeneca
|
|
gptkbp:marketedIn
|
gptkb:Asia
gptkb:Australia
gptkb:Canada
gptkb:Europe
gptkb:United_States
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:patentExpired
|
2015 (US)
|
|
gptkbp:pregnancyCategory
|
Category C (US)
|
|
gptkbp:relatedTo
|
gptkb:omeprazole
gptkb:pantoprazole
gptkb:lansoprazole
gptkb:rabeprazole
gptkb:dexlansoprazole
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
abdominal pain
constipation
headache
dry mouth
|
|
gptkbp:usedFor
|
gptkb:Zollinger-Ellison_syndrome
gptkb:erosive_esophagitis
gptkb:gastroesophageal_reflux_disease
gptkb:peptic_ulcer_disease
|
|
gptkbp:bfsParent
|
gptkb:AstraZeneca_US
gptkb:AstraZeneca_AB
|
|
gptkbp:bfsLayer
|
6
|