Zollinger-Ellison syndrome

GPTKB entity

Properties (58)
Predicate Object
gptkbp:instanceOf syndrome
gptkbp:associated_with nutritional support
chronic diarrhea
MEN1 syndrome
abdominal cramping
hyperplasia_of_gastric_mucosa
gptkbp:associatedWith gastrinoma
gptkbp:can_be adults
secretin stimulation test
gptkbp:causedBy neuroendocrine tumors
gastric acid hypersecretion
gptkbp:demographics rare
gptkbp:descendant in some cases
gptkbp:designatedAs a rare endocrine disorder
gptkbp:diseaseResistance biopsy
endoscopy
serum gastrin test
https://www.w3.org/2000/01/rdf-schema#label Zollinger-Ellison syndrome
gptkbp:impact stress
surgery
medication
certain medications
gastrointestinal system
proton pump inhibitors
gptkbp:introduced 1955
gptkbp:is_a functional gastrointestinal disorder
gptkbp:is_characterized_by excessive gastric acid production
recurrent ulcers
gptkbp:is_featured_in peptic ulcer disease
gptkbp:is_governed_by gastroenterologists
gptkbp:is_monitored_by gastrin levels
gptkbp:is_studied_in malignancy
gptkbp:is_used_in middle-aged individuals
chronic pancreatitis
gptkbp:leads malnutrition
peptic ulcers
gptkbp:namedAfter gptkb:John_Zollinger
gptkb:Eugene_Ellison
gptkbp:performedBy children
gptkbp:requires gptkb:CT_scan
MRI
long-term management
gptkbp:symptoms nausea
abdominal pain
diarrhea
gptkbp:threats gastrointestinal bleeding
intestinal obstruction
gptkbp:was_a_result_of requires multidisciplinary care
can lead to significant morbidity
can affect quality of life
can be challenging to treat
gastrin-secreting tumors
may require lifestyle changes
gptkbp:works_with weight loss
gastroesophageal reflux disease
esophagitis
gptkbp:worksWith lanreotide
octreotide