Nerve growth factor beta chain

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:NGFB gptkb:beta-NGF NGF beta
gptkbp:category	growth factor neurotrophin
gptkbp:discoveredBy	gptkb:Rita_Levi-Montalcini gptkb:Stanley_Cohen
gptkbp:encodedBy	NGF gene
gptkbp:foundIn	gptkb:Mus_musculus gptkb:Homo_sapiens
gptkbp:function	promotes survival and differentiation of neurons binds to TrkA receptor binds to p75NTR receptor
https://www.w3.org/2000/01/rdf-schema#label	Nerve growth factor beta chain
gptkbp:medicalUse	investigated for peripheral neuropathy investigated for Alzheimer's disease
gptkbp:molecularWeight	13.5 kDa
gptkbp:mutationAssociatedWith	gptkb:hereditary_sensory_and_autonomic_neuropathy_type_V
gptkbp:OMIM	162030
gptkbp:partOf	gptkb:nerve_growth_factor
gptkbp:PDB	gptkb:1BET gptkb:1SGF
gptkbp:producedBy	submaxillary gland (mouse) various tissues in mammals
gptkbp:requires	sympathetic nervous system development sensory neuron survival
gptkbp:role	pain modulation inflammation neurogenesis neuronal maintenance
gptkbp:sequence	gptkb:UniProt:P01138
gptkbp:structure	homodimer
gptkbp:UniProtID	gptkb:P01138
gptkbp:bfsParent	gptkb:beta-NGF_protein
gptkbp:bfsLayer	8