|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:NGF-beta
gptkb:Nerve_growth_factor_subunit_beta
|
|
gptkbp:discoveredBy
|
gptkb:Rita_Levi-Montalcini
gptkb:Stanley_Cohen
|
|
gptkbp:discoveredIn
|
1950s
|
|
gptkbp:EC_number
|
none (not an enzyme)
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:fullName
|
gptkb:beta-Nerve_Growth_Factor
|
|
gptkbp:function
|
promotes growth and survival of neurons
|
|
gptkbp:gene
|
gptkb:NGF
|
|
gptkbp:GO
|
GO:0005169 (nerve growth factor receptor binding)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
beta-NGF
|
|
gptkbp:locatedOnChromosome
|
chromosome 1p13.1 (human)
|
|
gptkbp:molecularWeight
|
~26 kDa
|
|
gptkbp:OMIM
|
162030
|
|
gptkbp:orthologIn
|
gptkb:mouse_beta-NGF
gptkb:rat_beta-NGF
|
|
gptkbp:PDB
|
gptkb:1BET
|
|
gptkbp:recipient
|
gptkb:TrkA
gptkb:p75NTR
|
|
gptkbp:relatedTo
|
neurotrophin family
|
|
gptkbp:role
|
wound healing
pain modulation
immune response
|
|
gptkbp:sequence
|
polypeptide
|
|
gptkbp:significance
|
gptkb:Alzheimer's_disease
peripheral neuropathy
chronic pain
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:UniProtID
|
gptkb:P01138
|
|
gptkbp:usedIn
|
neuroscience research
|
|
gptkbp:bfsParent
|
gptkb:Nerve_Growth_Factor
|
|
gptkbp:bfsLayer
|
7
|