Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:NGF-beta
gptkb:Nerve_growth_factor_beta_chain |
| gptkbp:discoveredBy |
gptkb:Rita_Levi-Montalcini
gptkb:Stanley_Cohen |
| gptkbp:discoveredIn |
1950s
|
| gptkbp:encodedBy |
NGF gene
|
| gptkbp:foundIn |
gptkb:human
gptkb:mouse right |
| gptkbp:fullName |
gptkb:beta-Nerve_Growth_Factor
|
| gptkbp:function |
promotes growth and survival of neurons
involved in neurogenesis regulates pain perception |
| gptkbp:GO_term |
GO:0007267 (cell-cell signaling)
GO:0007399 (nervous system development) GO:0008081 (nerve growth factor receptor binding) |
| https://www.w3.org/2000/01/rdf-schema#label |
beta-NGF protein
|
| gptkbp:medicalUse |
investigated for neurodegenerative diseases
studied in pain management |
| gptkbp:molecularWeight |
~26 kDa
|
| gptkbp:PDB |
gptkb:1BET
|
| gptkbp:recipient |
gptkb:TrkA
gptkb:p75NTR |
| gptkbp:relatedTo |
gptkb:nerve_growth_factor_family
|
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
gptkb:P01138
|
| gptkbp:bfsParent |
gptkb:NGFB
|
| gptkbp:bfsLayer |
7
|