Statements (123)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:Li-Fraumeni_syndrome
Various cancers |
| gptkbp:biologicalProcess |
DNA-binding
Transcription factor activity |
| gptkbp:function |
Acts as a tumor suppressor in many tumor types
Induces growth arrest or apoptosis depending on the physiological circumstances and cell type |
| gptkbp:gene |
gptkb:TP53
|
| https://www.w3.org/2000/01/rdf-schema#label |
UniProt:P01138
|
| gptkbp:locatedOnChromosome |
17p13.1
|
| gptkbp:name |
gptkb:Cellular_tumor_antigen_p53
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
Apoptosis
Cell cycle regulation |
| gptkbp:postTranslationalModification |
Phosphorylation
Acetylation Ubiquitination |
| gptkbp:products |
Isoform 1
Isoform 2 Isoform 3 Isoform 4 Isoform 10 Isoform 11 Isoform 12 Isoform 13 Isoform 14 Isoform 15 Isoform 16 Isoform 17 Isoform 18 Isoform 19 Isoform 20 Isoform 21 Isoform 22 Isoform 23 Isoform 24 Isoform 25 Isoform 26 Isoform 27 Isoform 28 Isoform 29 Isoform 30 Isoform 5 Isoform 6 Isoform 7 Isoform 8 Isoform 9 Isoform 100 Isoform 31 Isoform 32 Isoform 33 Isoform 34 Isoform 35 Isoform 36 Isoform 37 Isoform 38 Isoform 39 Isoform 40 Isoform 41 Isoform 42 Isoform 43 Isoform 44 Isoform 45 Isoform 46 Isoform 47 Isoform 48 Isoform 49 Isoform 50 Isoform 51 Isoform 52 Isoform 53 Isoform 54 Isoform 55 Isoform 56 Isoform 57 Isoform 58 Isoform 59 Isoform 60 Isoform 61 Isoform 62 Isoform 63 Isoform 64 Isoform 65 Isoform 66 Isoform 67 Isoform 68 Isoform 69 Isoform 70 Isoform 71 Isoform 72 Isoform 73 Isoform 74 Isoform 75 Isoform 76 Isoform 77 Isoform 78 Isoform 79 Isoform 80 Isoform 81 Isoform 82 Isoform 83 Isoform 84 Isoform 85 Isoform 86 Isoform 87 Isoform 88 Isoform 89 Isoform 90 Isoform 91 Isoform 92 Isoform 93 Isoform 94 Isoform 95 Isoform 96 Isoform 97 Isoform 98 Isoform 99 |
| gptkbp:sequence |
393
|
| gptkbp:subcellularLocation |
gptkb:Mitochondrion
gptkb:Nucleus gptkb:Cytoplasm |
| gptkbp:bfsParent |
gptkb:nerve_growth_factor_beta_chain
|
| gptkbp:bfsLayer |
8
|