|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
MOP4
bHLHe9
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:depression
sleep disorders
mood disorders
sleep phase disorder
|
|
gptkbp:component
|
gptkb:nucleus
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
NPAS2 protein
|
|
gptkbp:Entrez_Gene_ID
|
4861
ENSG00000170485
|
|
gptkbp:expressedIn
|
brain
liver
circadian
|
|
gptkbp:fullName
|
Neuronal PAS domain protein 2
|
|
gptkbp:function
|
transcription factor
regulation of circadian rhythm
transcription regulation
DNA binding
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOProcess
|
regulation of transcription
circadian rhythm
|
|
gptkbp:HGNC_ID
|
7892
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NPAS2
|
|
gptkbp:interactsWith
|
gptkb:CLOCK
gptkb:CRY1
gptkb:PER2
ARNTL (BMAL1)
|
|
gptkbp:length
|
1390 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 2
2q11.2
|
|
gptkbp:molecularWeight
|
155 kDa
|
|
gptkbp:mutationAssociatedWith
|
altered circadian behavior
|
|
gptkbp:OMIM
|
603347
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:ARNTL
gptkb:CLOCK
|
|
gptkbp:orthologInMouse
|
Npas2
|
|
gptkbp:proteinFamily
|
PAS domain
bHLH domain
bHLH-PAS family
PAC domain
|
|
gptkbp:regulates
|
E-box elements
circadian gene expression
|
|
gptkbp:regulatoryElement
|
gptkb:E-box
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
Q99743
|
|
gptkbp:bfsParent
|
gptkb:bHLH-PAS
|
|
gptkbp:bfsLayer
|
7
|