Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:TTF-1
gptkb:Thyroid_transcription_factor_1 |
| gptkbp:associatedWith |
gptkb:benign_hereditary_chorea
gptkb:brain-lung-thyroid_syndrome respiratory distress congenital hypothyroidism |
| gptkbp:discoveredBy |
Lazzaro et al.
|
| gptkbp:encodes |
gptkb:Homeobox_protein_Nkx-2.1
|
| gptkbp:Entrez_Gene_ID |
7080
ENSG00000136352 |
| gptkbp:expressedIn |
gptkb:thyroid
gptkb:cancer brain |
| gptkbp:firstDescribed |
1991
|
| gptkbp:function |
transcription factor
|
| gptkbp:hasDNA-bindingDomain |
homeodomain
|
| gptkbp:HGNC_ID |
HGNC:7838
|
| https://www.w3.org/2000/01/rdf-schema#label |
NKX2-1
|
| gptkbp:involvedIn |
lung development
forebrain development thyroid development |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_14
|
| gptkbp:OMIM |
600635
|
| gptkbp:orthologInMouse |
gptkb:Nkx2-1
|
| gptkbp:proteinFamily |
gptkb:NK2_homeobox_family
|
| gptkbp:regulates |
gptkb:thyroid_peroxidase
gptkb:SFTPB gptkb:SFTPC gptkb:thyroglobulin |
| gptkbp:UniProtID |
P43699
|
| gptkbp:bfsParent |
gptkb:NKX
|
| gptkbp:bfsLayer |
6
|