Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:TPO
|
| gptkbp:assayedBy |
anti-thyroid peroxidase antibody test
|
| gptkbp:cofactor |
hemoglobin
|
| gptkbp:EC_number |
1.11.1.8
|
| gptkbp:foundIn |
thyroid gland
|
| gptkbp:function |
involved in thyroid hormone synthesis
catalyzes iodination of tyrosine residues in thyroglobulin |
| gptkbp:gene |
TPO gene
|
| https://www.w3.org/2000/01/rdf-schema#label |
thyroid peroxidase
|
| gptkbp:locatedOnChromosome |
chromosome 2p25
|
| gptkbp:location |
apical membrane of thyroid follicular cells
|
| gptkbp:molecularWeight |
~100 kDa
|
| gptkbp:OMIM |
274500
|
| gptkbp:significance |
autoantigen in Graves' disease
autoantigen in Hashimoto's thyroiditis |
| gptkbp:substrate |
gptkb:thyroglobulin
hydrogen peroxide iodide |
| gptkbp:UniProtID |
P07202
|
| gptkbp:bfsParent |
gptkb:Thyroglobulin
|
| gptkbp:bfsLayer |
5
|