Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:TTF-1
NK2 homeobox 1 |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:benign_hereditary_chorea congenital hypothyroidism |
| gptkbp:discoveredBy |
Lazzaro et al.
|
| gptkbp:discoveredIn |
1991
|
| gptkbp:encodes |
NK2 homeobox 1 protein
|
| gptkbp:Entrez_Gene_ID |
7080
ENSG00000136352 |
| gptkbp:expressedIn |
gptkb:cancer
thyroid gland forebrain |
| gptkbp:function |
transcription factor
|
| gptkbp:HGNC_ID |
7836
|
| https://www.w3.org/2000/01/rdf-schema#label |
Nkx2-1
|
| gptkbp:involvedIn |
lung development
forebrain development thyroid development |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_14
|
| gptkbp:OMIM |
600635
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Nkx2-1
|
| gptkbp:proteinFamily |
homeobox domain
|
| gptkbp:regulates |
surfactant protein genes
thyroglobulin gene thyroid peroxidase gene NK2 family |
| gptkbp:UniProtID |
P43699
|
| gptkbp:bfsParent |
gptkb:NKX2-1
|
| gptkbp:bfsLayer |
7
|