Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:NKX2-1
gptkb:Thyroid_transcription_factor_1 |
| gptkbp:associatedWith |
gptkb:brain-lung-thyroid_syndrome
chorea congenital hypothyroidism lung carcinoma |
| gptkbp:encodedBy |
NKX2-1 gene
|
| gptkbp:Entrez_Gene_ID |
7080
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
transcription factor
regulates gene expression |
| gptkbp:HGNC_ID |
7838
|
| https://www.w3.org/2000/01/rdf-schema#label |
Homeobox protein Nkx-2.1
|
| gptkbp:involvedIn |
lung development
forebrain development thyroid development |
| gptkbp:length |
401 amino acids
|
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
chromosome 14q13.3
|
| gptkbp:molecularWeight |
38 kDa
|
| gptkbp:motif |
homeobox domain
|
| gptkbp:OMIM |
600635
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:PDB |
1V6O
|
| gptkbp:regulates |
surfactant protein genes
thyroglobulin gene thyroid peroxidase gene thyroid-stimulating hormone receptor gene |
| gptkbp:UniProtID |
P43699
|
| gptkbp:bfsParent |
gptkb:NKX2-1
|
| gptkbp:bfsLayer |
7
|