Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
NCK adaptor protein 1
NCK alpha |
| gptkbp:discoveredBy |
Pawson T et al.
|
| gptkbp:domain |
SH2 domain
SH3 domain |
| gptkbp:encodes |
Cytoplasmic protein NCK1
|
| gptkbp:Entrez_Gene_ID |
4690
ENSG00000163794 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
adaptor protein in signal transduction
|
| gptkbp:HGNC_ID |
7666
|
| https://www.w3.org/2000/01/rdf-schema#label |
NCK1
|
| gptkbp:interactsWith |
gptkb:EGFR
gptkb:PAK1 gptkb:PDGFR gptkb:SOS1 WASL |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_3
|
| gptkbp:molecularWeight |
47 kDa
|
| gptkbp:OMIM |
600495
|
| gptkbp:orthologInMouse |
Nck1
|
| gptkbp:phosphorylates |
tyrosine residues
|
| gptkbp:regulates |
cell proliferation
cell migration cell adhesion |
| gptkbp:roleInPathway |
receptor tyrosine kinase signaling
actin cytoskeleton organization |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
P16333
|
| gptkbp:bfsParent |
gptkb:PAK1
gptkb:CDC42 |
| gptkbp:bfsLayer |
7
|