|
gptkbp:instanceOf
|
neurodegenerative disease
|
|
gptkbp:abbreviation
|
gptkb:MSA
|
|
gptkbp:affects
|
movement
autonomic nervous system
|
|
gptkbp:average_survival_after_diagnosis
|
6 to 10 years
|
|
gptkbp:category
|
gptkb:synucleinopathy
autonomic disorder
rare disease
movement disorder
|
|
gptkbp:cause
|
unknown
|
|
gptkbp:diagnosedBy
|
clinical evaluation
MRI
|
|
gptkbp:differentialDiagnosis
|
gptkb:Parkinson's_disease
gptkb:corticobasal_degeneration
gptkb:progressive_supranuclear_palsy
|
|
gptkbp:firstDescribed
|
1960s
|
|
gptkbp:frequency
|
rare
|
|
gptkbp:has_no_cure
|
true
|
|
gptkbp:hasOrphanetID
|
gptkb:ORPHA102
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Multiple system atrophy
|
|
gptkbp:ICD-10_code
|
G90.3
|
|
gptkbp:MeSH_ID
|
D020754
|
|
gptkbp:notableContributor
|
gptkb:Niall_Quinn
gptkb:Graham_Lees
|
|
gptkbp:OMIM
|
146500
|
|
gptkbp:onset
|
adulthood
|
|
gptkbp:pathology
|
glial cytoplasmic inclusions
|
|
gptkbp:prognosis
|
poor
|
|
gptkbp:progression
|
progressive
|
|
gptkbp:protein_involved
|
gptkb:alpha-synuclein
|
|
gptkbp:relatedTo
|
gptkb:Shy-Drager_syndrome
gptkb:Parkinson's_disease
|
|
gptkbp:riskFactor
|
age
male sex
|
|
gptkbp:subspecies
|
gptkb:MSA-C
gptkb:MSA-P
|
|
gptkbp:symptom
|
gptkb:orthostatic_hypotension
autonomic dysfunction
erectile dysfunction
parkinsonism
urinary incontinence
cerebellar ataxia
|
|
gptkbp:treatment
|
supportive care
physical therapy
medications for symptoms
|
|
gptkbp:bfsParent
|
gptkb:Kerry_Simon
gptkb:Other_disorders_of_the_autonomic_nervous_system_(G90)
gptkb:Dementia_with_Lewy_Bodies
|
|
gptkbp:bfsLayer
|
7
|