gptkbp:instanceOf
|
neurodegenerative disease subtype
|
gptkbp:abbreviation
|
gptkb:Multiple_System_Atrophy_-_Parkinsonian_type
|
gptkbp:affects
|
gptkb:basal_ganglia
autonomic nervous system
|
gptkbp:associatedWith
|
alpha-synuclein accumulation
oligodendroglial cytoplasmic inclusions
|
gptkbp:averageSurvivalAfterDiagnosis
|
6-10 years
|
gptkbp:characterizedBy
|
autonomic dysfunction
parkinsonism
poor response to levodopa
|
gptkbp:commonAutonomicSymptoms
|
gptkb:orthostatic_hypotension
erectile dysfunction
urinary incontinence
|
gptkbp:commonMisdiagnosis
|
gptkb:Parkinson's_disease
|
gptkbp:commonMotorSymptoms
|
bradykinesia
postural instability
rigidity
|
gptkbp:diagnosedBy
|
clinical evaluation
MRI brain imaging
|
gptkbp:differentialDiagnosis
|
gptkb:Parkinson's_disease
gptkb:corticobasal_degeneration
gptkb:progressive_supranuclear_palsy
|
gptkbp:distinctFrom
|
gptkb:MSA-C
gptkb:Parkinson's_disease
|
gptkbp:firstDescribed
|
1960s
|
gptkbp:fullName
|
gptkb:Multiple_System_Atrophy_-_Parkinsonian_type
|
gptkbp:geneticStudies
|
rare
|
gptkbp:hasEpidemiology
|
slightly more common in men
|
gptkbp:hasNoCure
|
true
|
https://www.w3.org/2000/01/rdf-schema#label
|
MSA-P
|
gptkbp:ICD-10_code
|
G90.3
|
gptkbp:mortalityRate
|
high
|
gptkbp:neuropathology
|
gptkb:striatonigral_degeneration
glial cytoplasmic inclusions
|
gptkbp:onset
|
typically after age 50
|
gptkbp:prevalence
|
rare
|
gptkbp:prognosis
|
poor
|
gptkbp:progression
|
gptkb:fire
|
gptkbp:relatedTo
|
gptkb:MSA-C
|
gptkbp:riskFactor
|
unknown
|
gptkbp:subspecies
|
gptkb:Multiple_System_Atrophy
|
gptkbp:symptom
|
bradykinesia
postural instability
rigidity
autonomic failure
|
gptkbp:treatment
|
physical therapy
symptomatic management
autonomic support
|
gptkbp:bfsParent
|
gptkb:Multiple_System_Atrophy
gptkb:multiple_system_atrophy
|
gptkbp:bfsLayer
|
7
|