|
gptkbp:instanceOf
|
neurodegenerative disease
|
|
gptkbp:abbreviation
|
gptkb:Multiple_System_Atrophy,_Cerebellar_type
|
|
gptkbp:affects
|
gptkb:cerebellum
autonomic nervous system
brainstem
|
|
gptkbp:associatedWith
|
gptkb:olivopontocerebellar_atrophy
|
|
gptkbp:averageSurvival
|
6-10 years after onset
|
|
gptkbp:cause
|
unknown
|
|
gptkbp:characterizedBy
|
autonomic dysfunction
gait disturbance
cerebellar ataxia
dysarthria
|
|
gptkbp:diagnosedBy
|
clinical evaluation
MRI brain imaging
|
|
gptkbp:differentialDiagnosis
|
gptkb:Parkinson's_disease
gptkb:progressive_supranuclear_palsy
spinocerebellar ataxia
|
|
gptkbp:firstDescribed
|
1960s
|
|
gptkbp:fullName
|
gptkb:Multiple_System_Atrophy,_Cerebellar_type
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MSA-C
|
|
gptkbp:ICD-10_code
|
G90.3
|
|
gptkbp:mortalityRate
|
high
|
|
gptkbp:onset
|
adulthood
|
|
gptkbp:pathology
|
alpha-synuclein accumulation
glial cytoplasmic inclusions
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:prognosis
|
poor
|
|
gptkbp:progression
|
progressive
|
|
gptkbp:relatedTo
|
gptkb:MSA-P
|
|
gptkbp:riskFactor
|
age over 50
|
|
gptkbp:subspecies
|
gptkb:Multiple_System_Atrophy_(MSA)
|
|
gptkbp:symptom
|
gptkb:orthostatic_hypotension
slurred speech
impaired coordination
urinary incontinence
|
|
gptkbp:treatment
|
supportive care
physical therapy
medications for symptoms
|
|
gptkbp:bfsParent
|
gptkb:Multiple_System_Atrophy
gptkb:multiple_system_atrophy
|
|
gptkbp:bfsLayer
|
7
|