MutS family

GPTKB entity

Statements (26)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:conservedIn prokaryotes
eukaryotes
gptkbp:discoveredBy gptkb:Paul_Modrich
gptkbp:domain ATPase domain
DNA binding domain
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:function initiation of DNA repair
recognition of DNA mismatches
gptkbp:GO_term GO:0006298 (mismatch repair)
https://www.w3.org/2000/01/rdf-schema#label MutS family
gptkbp:involvedIn DNA mismatch repair
gptkbp:member gptkb:MSH2
gptkb:MSH6
gptkb:MSH3
MutS
MSH4
MSH5
gptkbp:mutationAssociatedWith gptkb:hereditary_nonpolyposis_colorectal_cancer
microsatellite instability
gptkbp:relatedTo MutL family
gptkbp:bfsParent gptkb:MSH2
gptkb:MSH6
gptkbp:bfsLayer 6