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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:GTBP
gptkb:MutS_homolog_6
G/T mismatch-binding protein
|
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gptkbp:associatedWith
|
gptkb:Lynch_syndrome
gptkb:hereditary_nonpolyposis_colorectal_cancer
|
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gptkbp:complex_name
|
MutSĪ±
|
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gptkbp:discoveredBy
|
1995
|
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gptkbp:encodedBy
|
MSH6 gene
|
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gptkbp:Entrez_Gene_ID
|
2956
ENSG00000116062
|
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gptkbp:formsComplexWith
|
gptkb:hMSH2
|
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gptkbp:function
|
DNA mismatch repair
|
|
gptkbp:gene
|
gptkb:MSH6
|
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gptkbp:GO_term
|
mismatch repair
DNA binding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
hMSH6
|
|
gptkbp:interactsWith
|
gptkb:MLH1
gptkb:PMS2
gptkb:PCNA
|
|
gptkbp:locatedOnChromosome
|
chromosome 2p16.3
|
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gptkbp:molecularWeight
|
160 kDa
|
|
gptkbp:mutationAssociatedWith
|
increased cancer risk
microsatellite instability
|
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gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
2O8B
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
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gptkbp:proteinFamily
|
gptkb:MutS_family
|
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gptkbp:RefSeq
|
NM_000179
|
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gptkbp:subcellularLocation
|
gptkb:nucleus
|
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gptkbp:UniProtID
|
P52701
|
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gptkbp:bfsParent
|
gptkb:MSH6
|
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gptkbp:bfsLayer
|
6
|