Mothers against decapentaplegic homolog 4
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:DPC4
gptkb:SMAD_family_member_4 |
| gptkbp:associatedWith |
gptkb:juvenile_polyposis_syndrome
colorectal cancer pancreatic cancer |
| gptkbp:discoveredBy |
1996
|
| gptkbp:Entrez_Gene_ID |
ENSG00000141646
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
signal transduction
transcription factor |
| gptkbp:gene |
gptkb:SMAD4
|
| gptkbp:HGNC_ID |
6770
|
| https://www.w3.org/2000/01/rdf-schema#label |
Mothers against decapentaplegic homolog 4
|
| gptkbp:interactsWith |
gptkb:SMAD2
gptkb:SMAD3 gptkb:TGFBR1 |
| gptkbp:involves |
gptkb:TGF-beta_signaling_pathway
|
| gptkbp:locatedOnChromosome |
chromosome 18q21.2
|
| gptkbp:molecularWeight |
60 kDa
|
| gptkbp:mutationAssociatedWith |
loss of function
|
| gptkbp:OMIM |
600993
|
| gptkbp:PDB |
gptkb:1U7V
|
| gptkbp:proteinFamily |
MH1 domain
MH2 domain |
| gptkbp:RefSeq |
NM_005359
|
| gptkbp:UniProtID |
gptkb:Q13485
|
| gptkbp:bfsParent |
gptkb:SMAD4
|
| gptkbp:bfsLayer |
6
|