Mitogen-activated protein kinase 13

URI: https://gptkb.org/entity/Mitogen-activated_protein_kinase_13
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:activatedBy gptkb:MAP2K3
gptkb:MAP2K6
gptkbp:alternativeName gptkb:MAPK13
gptkb:p38_delta
gptkbp:associatedWith gptkb:cancer
inflammatory diseases
gptkbp:biologicalProcess protein serine/threonine kinase activity
gptkbp:Entrez_Gene_ID gptkb:ENSG00000156711
5603
gptkbp:enzymeClassification gptkb:EC_2.7.11.24
gptkbp:expressedIn gptkb:cancer
gptkb:kidney
gptkb:small_intestine
pancreas
gptkbp:family gptkb:MAP_kinase_family
gptkbp:function signal transduction
inflammatory response
cellular response to stress
gptkbp:HGNC_ID gptkb:MAPK13
https://www.w3.org/2000/01/rdf-schema#label Mitogen-activated protein kinase 13
gptkbp:inhibitedBy gptkb:SB203580
gptkb:BIRB_796
gptkbp:involves gptkb:MAPK_signaling_pathway
stress-activated protein kinase pathway
gptkbp:length 365
gptkbp:locatedOnChromosome gptkb:chromosome_6
gptkbp:molecularWeight 41 kDa
gptkbp:OMIM 605431
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Mapk13
gptkbp:PDB 3GC8
4EYJ
gptkbp:phosphorylates transcription factors
Thr-180
Tyr-182
gptkbp:postTranslationalModification phosphorylation
gptkbp:product gptkb:MAPK13_gene
gptkbp:regulates apoptosis
cell differentiation
cell proliferation
gptkbp:subcellularLocation gptkb:nucleus
gptkb:cytoplasm
gptkbp:subfamily gptkb:p38_MAP_kinase_subfamily
gptkbp:UniProtID O15264
gptkbp:bfsParent gptkb:MAPK13
gptkb:p38_delta
gptkbp:bfsLayer 7