Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
monophenol monooxygenase
polyphenol oxidase |
| gptkbp:associatedWith |
oculocutaneous albinism type 1
|
| gptkbp:cofactor |
copper
|
| gptkbp:discoveredBy |
Friedrich W. Tiedemann
|
| gptkbp:discoveredIn |
1819
|
| gptkbp:EC_number |
1.14.18.1
|
| gptkbp:foundIn |
animals
fungi plants |
| gptkbp:function |
involved in melanin biosynthesis
catalyzes oxidation of phenols |
| gptkbp:gene |
gptkb:TYR
|
| gptkbp:gene_location_(human) |
chromosome 11q14-q21
|
| https://www.w3.org/2000/01/rdf-schema#label |
tyrosinase
|
| gptkbp:inhibitedBy |
gptkb:hydroquinone
azelaic acid arbutin kojic acid |
| gptkbp:location |
gptkb:melanosome
|
| gptkbp:molecularWeight |
~60 kDa
|
| gptkbp:product |
melanin
dopaquinone |
| gptkbp:structure |
gptkb:protein
|
| gptkbp:substrate |
gptkb:L-DOPA
gptkb:L-tyrosine |
| gptkbp:UniProtID |
P14679
|
| gptkbp:used_in |
gptkb:biotechnology
cosmetics industry food industry |
| gptkbp:bfsParent |
gptkb:melanocytes
gptkb:tyrosine_pathway |
| gptkbp:bfsLayer |
8
|