MT-CO1

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alsoKnownAs gptkb:COI
gptkb:COX1
gptkbp:conservedIn eukaryotes
gptkbp:discoveredBy Anderson et al.
gptkbp:discoveredIn 1981
gptkbp:encodes gptkb:cytochrome_c_oxidase_subunit_I
gptkbp:Entrez_Gene_ID 4512
gptkbp:essentialGene yes
gptkbp:expressedIn all human tissues
gptkbp:fullName gptkb:Mitochondrially_encoded_cytochrome_c_oxidase_I
gptkbp:function oxidative phosphorylation
electron transport chain
cytochrome-c oxidase activity
gptkbp:GOProcess oxidative phosphorylation
gptkbp:hasPseudogene no
gptkbp:HGNC_ID 7419
https://www.w3.org/2000/01/rdf-schema#label MT-CO1
gptkbp:involvedIn gptkb:mitochondrial_respiratory_chain_complex_IV
gptkbp:length 514
gptkbp:locatedIn gptkb:mitochondrial_DNA
gptkbp:locatedOnChromosome mitochondrial
gptkbp:location mitochondrial inner membrane
gptkbp:mutationAssociatedWith gptkb:Leigh_syndrome
gptkb:mitochondrial_complex_IV_deficiency
gptkbp:nucleotideSequence ATGGC...TAA (truncated)
gptkbp:numberOfExons 1
gptkbp:OMIM 516030
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:Danio_rerio
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
gptkbp:product gptkb:cytochrome_c_oxidase_subunit_I
gptkbp:proteinSequence MFINW...LFF (truncated)
gptkbp:RefSeq gptkb:NC_012920.1
gptkbp:sequence 1542
gptkbp:significance yes
gptkbp:startPoint 5904
7445
gptkbp:strand heavy
gptkbp:transcriptionDirection 5' to 3'
gptkbp:transcriptionProduct gptkb:gene
gptkbp:translatedInto gptkb:mitochondrial_cytochrome_c_oxidase_subunit_I_protein
gptkbp:translationProduct gptkb:cytochrome_c_oxidase_subunit_I
gptkbp:UniProtID gptkb:P00395
gptkbp:usedFor phylogenetic studies
species identification
gptkbp:usedIn DNA barcoding
gptkbp:bfsParent gptkb:P00441
gptkbp:bfsLayer 6