Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:ERK1/2
gptkb:p38_MAPK |
| gptkbp:alternativeName |
gptkb:MSK-1
gptkb:RPS6KA5 |
| gptkbp:discoveredBy |
1998
|
| gptkbp:fullName |
gptkb:Mitogen-_and_stress-activated_protein_kinase_1
|
| gptkbp:function |
serine/threonine-protein kinase
phosphorylates transcription factors regulates gene expression in response to stress and mitogens |
| gptkbp:gene |
gptkb:RPS6KA5
|
| https://www.w3.org/2000/01/rdf-schema#label |
MSK1
|
| gptkbp:locatedOnChromosome |
gptkb:14q32.2
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:molecularWeight |
90 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:mouse_MSK1
gptkb:rat_MSK1 |
| gptkbp:pathway |
gptkb:MAPK_signaling_pathway
stress response pathway |
| gptkbp:phosphorylates |
gptkb:CREB
gptkb:ATF1 gptkb:Histone_H3 |
| gptkbp:species |
gptkb:human
|
| gptkbp:structure |
contains two kinase domains
|
| gptkbp:UniProtID |
gptkb:O75582
|
| gptkbp:bfsParent |
gptkb:p38_MAPK_pathway
|
| gptkbp:bfsLayer |
6
|