Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
superfamily
|
| gptkbp:catalyzes |
transfer of phosphate group from ATP to substrate protein
|
| gptkbp:composedOf |
protein kinases
|
| gptkbp:discoveredBy |
gptkb:Edwin_G._Krebs
gptkb:Edmond_H._Fischer |
| gptkbp:domain |
protein kinase domain
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
gptkb:diabetes neurodegenerative diseases |
| gptkbp:EC_number |
2.7.11.-
|
| gptkbp:foundIn |
prokaryotes
eukaryotes |
| gptkbp:function |
phosphorylation
|
| https://www.w3.org/2000/01/rdf-schema#label |
protein kinase superfamily
|
| gptkbp:includes |
histidine kinases
serine/threonine kinases tyrosine kinases |
| gptkbp:InterPro |
gptkb:IPR000719
|
| gptkbp:NobelPrizeYear |
gptkb:1992_Nobel_Prize_in_Physiology_or_Medicine
|
| gptkbp:proteinFamily |
gptkb:PF00069
|
| gptkbp:role |
apoptosis
cell cycle regulation metabolism cell signaling growth and differentiation |
| gptkbp:studiedIn |
biochemistry
molecular biology |
| gptkbp:target |
kinase inhibitors
|
| gptkbp:bfsParent |
gptkb:RAF_kinase
|
| gptkbp:bfsLayer |
5
|